Won Son J, et al. More specifically, this medication is an option for people with a body mass index (BMI): Greater than 30 kg/m2 Greater than 27 kg/m2 + one or more weight-related condition Drug classes: Anorexiants, CNS stimulants. information highlighted below and resubmit the form. Phendimetrazine tartrate is a white, odorless crystalline powder. In a single-dose study comparing the exposures after oral administration of a combination capsule of 15 mg Phentermine and 92 mg topiramate to the exposures after oral administration of a 15 mg Phentermine capsule or a 92 mg topiramate capsule, there is no significant topiramate exposure change in the presence of Phentermine. endstream endobj 1531 0 obj <>/Metadata 26 0 R/Pages 1528 0 R/StructTreeRoot 41 0 R/Type/Catalog>> endobj 1532 0 obj <>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/StructParents 0/Tabs/S/TrimBox[0.0 0.0 630.0 702.0]/Type/Page>> endobj 1533 0 obj <>stream It is important to follow these instructions religiously. If obesity is impacting your fertility or reproductive health, or if you have a specific condition that affects weight (such as PCOS), your gynecologist may consider prescribing phentermine as a short-term weight management strategy. ), Cannot find a doctor in your network that prescribes phentermine. %PDF-1.6 % If we combine this information with your protected After the tablet has melted, swallow or take a sip of water. Keep from freezing. the current rules place time limitations on prescriptions that, many times, force physicians to stop a medication that is showing positive weight loss results. ). ). It should also not be taken within 14 days after taking an MAO inhibitor. 1 Learn about the most popular weight loss medications. State Medical Board of Ohio 30 E. Broad Street, 3rd Floor, Columbus, OH 43215-6127 (614) 466-3934 med.ohio.gov Of course, it is taken orally. Talk with your doctor before starting an exercise program. The recommended maximum dosage of Phentermine is 15 mg daily for patients with severe renal impairment (eGFR 15 to 29 mL/min/1.73m2). 4 0 obj Duromine is not funded by Pharmac, so patients pay $160-$200 per month when they present a standard prescription of 30mg daily - in addition to the GP consultation fee. 5 HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use ADIPEX-P safely and effectively. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient. Columbus, Ohio 43215 Phone: (614) 466-3934 Web: www.med.ohio.gov State Medical Board of Ohio 30 E . Below is a chart of body mass index (BMI) based on various heights and weights. hbbd``b`z$@D`]"@DeX- Bb V ``LA\F*? Phentermine Hydrochloride Tablets are indicated as a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity for patients with an initial body mass index 30 kg/m 2, or 27 kg/m 2 in the presence of other risk factors (e.g., hb``````>X,K10wdjdZ(`l Ro4' b2h>$:-9.AKL1}c$vEP;-@c=en`Y %YQh` &^ The overdose symptoms include: The side effects of Phentermine can lead to several symptoms that may impair certain functions in the patients body. These are two schedule- IV medications, phentermine/topiramate (Qsymia), and locaserin (Belviq), as well as non-controlled naltrexone hydrochloride/ buproprion hydrochloride (Contrave). Phentermine is not recommended for use in pediatric patients 16 years of age. Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. Phentermine has not been studied in patients with eGFR less than 15 mL/min/1.73m2, including end-stage renal disease requiring dialysis; avoid use in these populations. In 1968, three years after its release, Aminorex was withdrawn. The amount of medicine that you take depends on the strength of the medicine. Or it can help you feel full longer. Or it can help you feel full longer. For more information, the rule package submitted to the Common Sense Initiative (CSI) office for review can be found here:https://med.ohio.gov/LinkClick.aspx?fileticket=Q2JmI7o-3HI%3d&portalid=0, 2023 The Ohio State Medical Association. To provide you with the most relevant and helpful information, and understand which For oral dosage form (extended-release capsules): Adults and children 16 years of age and olderOne capsule once a day, taken before breakfast or 10 to 14 hours before sleeping. Phentermine is intended to help overweight and obese patients who have already tried losing weight with diet and exercise. Not only can losing weight harm an unborn baby during pregnancy, but the drug may also cause adverse effects. Phentermine is approved for short-term weight loss therapy. Create well-written care plans that meets your patient's health goals. For some patients, half tablet (18.75 mg) daily may be adequate, while in some cases it may be desirable to give half tablets (18.75 mg) two times a day. RPYcn@b[%XYK'Q %[.()GTkJ WCf.-i>n-oIzE*D40f#Gp'LcddmE8;>u?X"tO 1]M={4,ReC8E8Z Q1Lt$-XpFCrTJ Ohio has some of the strictest rules in the country and. What to offer the 99% of patients with severe obesity who do not undergo bariatric surgery? It is important not to perform activities that require a patient to be alert while experiencing mental impairment as an adverse effect. The combined drug is approved for long-term use. In some cases, especially when the health concern is not too serious, the doctor may prescribe the drug at lower doses spread throughout the day, instead of advising the patient to take one single dose every day. The Formulary can be accessed on the Board of Nursing website: www.nursing. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). However, if it is almost time for your next dose, skip the missed dose and go back to your . However, weight loss clinics are not the perfect solution. Burguera B, et al. (phentermine hydrochloride) orally disintegrating tablet C IV . Patients should be advised to report immediately any deterioration in exercise tolerance. CIV The drug is also available in regular capsules that are taken orally with a glass of water. They are usually real doctors who prescribe real phentermine without the now-mandatory face-to-face consultation. If the time is too close to the next dose, it is recommended to skip the dose they have missed. See Drug Abuse and Dependence (9) and Overdosage (10). Cardiovascular effects include arrhythmia, hypertension or hypotension, and circulatory collapse. The natural history of obesity is measured over several years, whereas the studies cited are restricted to a few weeks duration; thus, the total impact of drug-induced weight loss over that of diet alone must be considered clinically limited. Weight Loss Prescribing Rules Ohio Administrative Code 4731-11-04 and 4731-11-04.1 The medical board is currently reviewing its long-standing rules regarding prescribing controlled substances for the treatment of obesity. Phentermine is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, amphetamine (d- and dll-amphetamine). Therefore, coadministration of Phentermine and these drug products is not recommended. The most common side effects that patients experience include tremors, headaches, dizziness, dry mouth, diarrhea, constipation, upset stomach, feeling restless and being hyperactive. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Start with your primary care doctor and schedule an appointment to discuss weight. Phentermine was later provided to patients in combination with dexfenfluramine and fenfluramine as a more powerful appetite suppressant that could also act as a fat burner. Apart from these brand names, other brands that contain the drug as part of their multi-ingredient formula also exist and the most popular one is Qsymia. N;d0)zQ|,]8EtXy(En"GX omjU3Y3>kfkYHYi]-zhm{= o`i$G1BK%?9Z+(dm`mKt,?;6K@Q 7}}*Tw>7BkKsJ;E|Viexb T-3j%5QB%wI5'$5oB :h*C"Q7yjTzLO%6QS/u>HX 4DGz*A!1*p"7$-joX2YF8ht@\l[&LS$FU=udM&y.l_ Serious regurgitant cardiac valvular disease, primarily affecting the mitral, aortic and/or tricuspid valves, has been reported in otherwise healthy persons who had taken a combination of Phentermine with fenfluramine or dexfenfluramine for weight loss. Unpublished raw data. Before writing a phentermine prescription, he or she will evaluate your: While any doctor can prescribe phentermine, not all doctors feel comfortable doing so. To avoid trouble with sleeping, take the last dose of the day about 4 to 6 hours before bedtime, unless your doctor tells you otherwise. Generic name: Phentermine hydrochloride endstream endobj 105 0 obj <> endobj 106 0 obj <>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI]>>/Rotate 0/Type/Page>> endobj 107 0 obj <>stream The usual adult dose is one tablet (37.5 mg) daily, as prescribed by the physician, administered before breakfast or 1 to 2 hours after breakfast. Mayo Clinic Proceedings. Phentermine hydrochloride/topiramate. Since 1997, allnurses is trusted by nurses around the globe. endstream endobj startxref The following information includes only the average doses of this medicine. Patients must be instructed on how much Phentermine to take, and when and how to take it [see Dosage and Administration (2)]. potentially hazardous activities such as operating machinery or driving FULL PRESCRIBING INFORMATION in the presence of other risk factors (e.g., controlled hypertension, 333-33-100411 Tasks 35 Acidification of the urine increases Phentermine excretion. Systemic exposure of Phentermine may increase up to 91%, 45%, and 22% in patients with severe, moderate, and mild renal impairment, respectively [see Dosage and Administration (2.2) and Use in Specific Populations (8.6)]. These are two schedule- IV medications, phentermine/topiramate (Qsymia), and locaserin (Belviq), as well as non-controlled naltrexone hydrochloride/ buproprion hydrochloride (Contrave). Because pediatric obesity is a chronic condition requiring long-term treatment, the use of this product, approved for short-term therapy, is not recommended. She is passionate about promoting health at any size. Phentermine has been linked to many complications; knowing these details will help patients minimize their risk of experiencing such unwanted scenarios. 1530 0 obj <> endobj This medicine is available in four forms: capsules, disintegrating tablets, extended-release capsules, and tablets. Facts & Comparisons eAnswers. But regarding phentermine monotherapy, phentermine hydrochloride (HCl) is a sympathomimetic Drug Enforcement Agency (DEA) scheduled IV drug approved as an anti-obesity medication and marketed in the US since 1959 (See Table 1).The reported weight reduction efficacy of phentermine [10] derived from . Patients who have been on a Phentermine program should not suddenly stop using the drug. Doctors often prescribe a dose of 5-HTP and vitamin B12 with a Phentermine prescription in order to enhance its effects and to relieve some side effects. The CPG determination is specific to Qsymin, Belviq and Contrave only. HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use . IBM Micromedex. 100 TABLETS Since Phentermine is a drug that contains chemical compounds, it is important to know about all of the risks that are involved with its use and precautions a person should be aware of before the consumption. Numerous side effects have been linked to the use of Phentermine. Highlighted below are the topics discussed at the meeting that OSMA is closely following. Adults and children 17 years of age and older15 to 30 milligrams (mg) once a day, taken at approximately 2 hours after breakfast. Mayo Clinic does not endorse companies or products. Instead of simply quitting the program, a patient should rather consult a healthcare provider about quitting. Get the best fitness, food, and weight loss tips to succeed on your journey! BMI is calculated by taking the patients weight, in kilograms (kg), divided by the patients height, in meters (m), squared. The possibility of an association between valvular heart disease and the use of Phentermine alone cannot be ruled out; there have been rare cases of valvular heart disease in patients who reportedly have taken Phentermine alone. Ask your healthcare professional how you should dispose of any medicine you do not use. Use of Phentermine is contraindicated during or within 14 days following the administration of monoamine oxidase inhibitors because of the risk of hypertensive crisis. However, the medication does have a considerable street value. (2019, May 03). You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. United Nations Office on Drugs and Crime.